Name | cirsimaritin |
Synonyms | Skrofulein Scrophulein cirsimaritin 6-Methoxygenkwanin 4',5-Dihydroxy-6,7-dimethoxyflavone 5-Hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy- |
CAS | 6601-62-3 |
Molecular Formula | C17H14O6 |
Molar Mass | 314.29 |
Density | 1.402±0.06 g/cm3(Predicted) |
Melting Point | 257 °C |
Boling Point | 563.6±50.0 °C(Predicted) |
Solubility | Methanol; DMSO |
Appearance | Yellow powder |
pKa | 6.34±0.40(Predicted) |
Storage Condition | -20°C |
MDL | MFCD00238561 |
In vivo study | Cirsimaritin significantly reduces the anxiety in mice. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg), indicating that the high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds. |
Risk Codes | R25 - Toxic if swallowed R50 - Very Toxic to aquatic organisms |
Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 2811 6.1 / PGIII |
WGK Germany | 3 |
biological activity | Cirsimaritin can weakly target the benzodiazepine site on the GABAA receptor, and has antidepressant, anti Anxiety, anti inoculation and other activities. |